DGIdb - ESKETAMINE HYDROCHLORIDE Drug Record

ESKETAMINE HYDROCHLORIDE chembl:CHEMBL2364609 Approved

Alternate Names:

SPRAVATO

AM-101

ESKETAMINE HCL

Drug Info:

FDA Approval not approved

Drug Class Small molecule

Drug Indications for treatment of tinnitus

(0 More Sources)

Publications:

ESKETAMINE HYDROCHLORIDE GRIN2C

Interaction Score: 0.77

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name AM-101

Novel drug target Novel Target

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
ESKETAMINE HYDROCHLORIDE GRIN3B

Interaction Score: 0.74

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name AM-101

Novel drug target Established target

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
ESKETAMINE HYDROCHLORIDE GRIN2D

Interaction Score: 0.71

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

Trial Name AM-101

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
ESKETAMINE HYDROCHLORIDE GRIN3A

Interaction Score: 0.59

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

Trial Name AM-101

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
ESKETAMINE HYDROCHLORIDE GRIN2B

Interaction Score: 0.46

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name AM-101

Novel drug target Established target

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
ESKETAMINE HYDROCHLORIDE GRIN1

Interaction Score: 0.43

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

Trial Name AM-101

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
ESKETAMINE HYDROCHLORIDE GRIN2A

Interaction Score: 0.29

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

TdgClinicalTrial: AM-101
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications for treatment of tinnitus

Drug Class Small molecule

FDA Approval not approved

Publications:
ChemblDrugs: chembl:CHEMBL2364609
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
ChemblInteractions: CHEMBL2364609
- Version: chembl_23
Alternate Names:

Drug Info:

Publications:

FDA Approval	not approved
Drug Class	Small molecule
Drug Indications	for treatment of tinnitus

Trial Name	AM-101
Novel drug target	Novel Target
Mechanism of Interaction	Glutamate [NMDA] receptor negative allosteric modulator

Mechanism of Interaction	Glutamate [NMDA] receptor negative allosteric modulator
Direct Interaction	yes
Trial Name	AM-101

SPRAVATO
AM-101
ESKETAMINE HCL

ESKETAMINE HYDROCHLORIDE Drug Record

ESKETAMINE HYDROCHLORIDE chembl:CHEMBL2364609 Approved

Alternate Names:

Drug Info:

Publications:

ESKETAMINE HYDROCHLORIDE GRIN2C

Interaction Types & Directionality: n/a

Interaction Info: Trial Name AM-101 Novel drug target Novel Target Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions

ESKETAMINE HYDROCHLORIDE GRIN3B

Interaction Types & Directionality: n/a

Interaction Info: Trial Name AM-101 Novel drug target Established target Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions

ESKETAMINE HYDROCHLORIDE GRIN2D

Interaction Types & Directionality: n/a

Interaction Info: Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator Direct Interaction yes Trial Name AM-101

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions

ESKETAMINE HYDROCHLORIDE GRIN3A

Interaction Types & Directionality: n/a

Interaction Info: Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator Direct Interaction yes Trial Name AM-101

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions

ESKETAMINE HYDROCHLORIDE GRIN2B

Interaction Types & Directionality: n/a

Interaction Info: Trial Name AM-101 Novel drug target Established target Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions

ESKETAMINE HYDROCHLORIDE GRIN1

Interaction Types & Directionality: n/a

Interaction Info: Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator Direct Interaction yes Trial Name AM-101

PMIDs: None found

Sources: TdgClinicalTrial ChemblInteractions

ESKETAMINE HYDROCHLORIDE GRIN2A

Interaction Types & Directionality: n/a

Interaction Info: Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

TdgClinicalTrial: AM-101

Alternate Names:

Drug Info: Drug Indications for treatment of tinnitus Drug Class Small molecule FDA Approval not approved

Publications:

ChemblDrugs: chembl:CHEMBL2364609

Alternate Names:

Drug Info:

Publications:

ChemblInteractions: CHEMBL2364609

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name AM-101

Novel drug target Novel Target

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name AM-101

Novel drug target Established target

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

Trial Name AM-101

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

Trial Name AM-101

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name AM-101

Novel drug target Established target

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

Trial Name AM-101

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Mechanism of Interaction Glutamate [NMDA] receptor negative allosteric modulator

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Drug Info:

Drug Indications for treatment of tinnitus

Drug Class Small molecule

FDA Approval not approved